Thyroid Peroxidase and Thyroglobulin Antibodies (Hashimoto's & Graves Disease Screening)

Thyroid Peroxidase (TPO)

This test checks for elevated antibodies created against the thyroid peroxidase (TPO), an enzyme that helps produce hormones. Therefore, if antibodies are detected with this test, it can indicate thyroid-related autoimmune disorders, like Hashimoto’s. Comparing this test with abnormal levels of thyroid-stimulating hormone may be a sign of Graves’ disease.

Thyroglobulin Antibodies (TgAb)

This test checks for antibodies created against the thyroglobulin, a protein produced and used by the thyroid gland to make T3 and T4 hormones, which control metabolism and tissue/cell growth. If present, it may indicate thyroid-related autoimmune disorders, like Hashimoto’s.